428 HCQ COVID-19 studies, 329 peer reviewed, 352 comparing treatment and control groups. HCQ is not effective when used very late with high dosages over a long period (RECOVERY/SOLIDARITY), effectiveness improves with earlier usage and improved dosing. Early treatment consistently shows positive effects. Negative evaluations typically ignore treatment time, often focusing on a subset of late stage studies. In Vitro evidence made some believe that therapeutic levels would not be attained, however that was incorrect, e.g. see [Ruiz][...] HCQ/CQ has been officially adopted for early treatment in all or part of 35 countries (52 including non-government medical organizations). Submit updates/corrections.
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