"Omicron bites hard in the UKHSA Vaccine Surveillance report this week, as unadjusted vaccine effectiveness against infection (calculated from the raw data) plummets across all age groups in the month ending January 2nd 2022. The revival in some age groups from the third doses has now been almost completely cancelled out, as all age groups above 18 years go negative again. Those in their 40s hit a new low of minus-151% (negative vaccine effectiveness means the vaccinated are more likely to be infected than the unvaccinated; a vaccine effectiveness of minus-100% means the vaccinated are twice as likely to be infected as the unvaccinated). There is a sharp drop for under-18s for the first time as well, with unadjusted vaccine effectiveness more than halving in a fortnight, collapsing from 79% to 38% (there was no report last week due to the Christmas holiday)."
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